Compound Reference

SLU-PP-332

An ERRα agonist studied as an exercise-mimetic

Metabolic researchEvidence: preclinicalRUO · not approved
Research Use Only. Not an approved medicine and not for human use. Educational only — no dosing or medical advice.

What it is

SLU-PP-332 is a small molecule (not a peptide) studied as an agonist of the estrogen-related receptor α (ERRα), marketed in research circles as an "exercise mimetic."

Proposed mechanism

ERRα regulates mitochondrial and oxidative-metabolism genes; agonizing it is proposed to increase fat oxidation and endurance in rodents without exercise.1 This is preclinical.

State of the evidence

Regulatory & status

References

  1. ERRα agonism / exercise-mimetic research. PubMed: SLU-PP-332

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