Compound Reference

Methylene Blue (Oral 25 mg)

A century-old dye & redox agent (FDA-approved for methemoglobinemia)

Mitochondrial researchEvidence: approved (specific) + emergingFDA-approved (specific indication)
Approved drug — used here for education. This is an approved/prescription medicine in at least one region; "research"/compounded versions sold as chemicals are a separate, riskier thing. Not medical advice.

What it is

Methylene blue is a synthetic dye (not a peptide) and one of the oldest drugs — FDA-approved to treat methemoglobinemia, and studied at low doses for mitochondrial/cognitive effects.

Proposed mechanism

At low doses it acts as an alternative electron carrier in the mitochondrial electron-transport chain and has antioxidant/redox effects; it is also a potent MAO inhibitor (a key drug-interaction caution).1

State of the evidence

Regulatory & status

References

  1. Methylene blue pharmacology (literature). PubMed: methylene blue

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For educational and research purposes only. This content is not medical advice. Methylene blue is a drug with serious interactions; use only under a licensed professional. Free Peptide University does not sell compounds.