A C-terminal α-MSH tripeptide with anti-inflammatory research
Immune / healingEvidence: preclinicalRUO · not approved
Research Use Only. Not an approved medicine and not for human use. Educational only — no dosing or medical advice.
What it is
KPV is a tripeptide (lysine-proline-valine) corresponding to the C-terminus of α-MSH, studied for anti-inflammatory effects, especially in gut models.
Proposed mechanism
It is reported to reduce inflammatory signaling (e.g., NF-κB pathway) in intestinal and skin models, without the pigmentation effects of full α-MSH.1
State of the evidence
Preclinical anti-inflammatory data; no Phase III.
Regulatory & status
Not approved; RUO.
Reconstitution (reference only)
Lab-handling reference only — not a preparation or dosing instruction: 2.5 mL (250 units) reconstitution solution per 10 mg vial. See the reconstitution calculator for the arithmetic. This page does not provide dosing guidance.
For educational and research purposes only. This content is not medical advice. Compounds referenced are research use only and not intended to diagnose, treat, cure, or prevent any disease. Free Peptide University does not sell compounds.