Compound Reference

5-Amino-1MQ

A small-molecule NNMT inhibitor studied in metabolism

Metabolic researchEvidence: preclinicalRUO · not approved
Research Use Only. Not an approved medicine and not for human use. Educational only — no dosing or medical advice.

What it is

5-Amino-1MQ is a small molecule (not a peptide) studied as an inhibitor of the enzyme NNMT (nicotinamide N-methyltransferase), which is linked to fat-cell metabolism and cellular NAD⁺ handling.

Proposed mechanism

By inhibiting NNMT, it is proposed in animal/cell models to raise cellular NAD⁺ and shift adipocyte energy metabolism toward fat breakdown.1 This is a preclinical hypothesis, not a demonstrated human effect.

State of the evidence

Regulatory & status

Reconstitution (reference only)

Lab-handling reference only — not a preparation or dosing instruction: 2 mL (200 units) reconstitution solution per 10 mg vial. See the reconstitution calculator for the arithmetic. This page does not provide dosing guidance.

References

  1. NNMT inhibition & metabolism (literature). PubMed: 5-Amino-1MQ

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